This is an archived handbook for a previous year. The current undergraduate and postgraduate handbooks can be viewed using the links above.
Undergraduate Handbook 2006-2007 (archived)
Module CHEM4211: BIOACTIVE CHEMISTRY 4
Department: Chemistry
CHEM4211: BIOACTIVE CHEMISTRY 4
| Type | Level | Credits | Availability | Module Cap | Location |
|---|---|---|---|---|---|
| Tied | 4 | 20 | Available in 2006/2007 | None. | Durham |
Tied To
Pre-requisites
- Bioactive Chemistry 3 (CHEM3211), Advanced Organic Chemistry (CHEM3031) AND Biological Chemistry (CHEM2051).
Corequisites
- Research Skills (CHEM4081).
Excluded Combinations
- Core Chemistry 4 (CHEM4311) AND Contemporary Chemistry (CHEM4321).
Aims
- To build on material taught at level three and provide students with an advanced overview of more specialised areas.
Content
- Modern synthetic methodology.
- Principles of enantioselective synthesis.
- Applied organic synthesis.
- Medicinal chemistry OR Macromolecular chemistry.
Learning Outcomes
Subject-specific Knowledge
- appreciate the problems involved in target synthesis of organic molecules, apply retrosynthetic analysis to their synthesis and make an informed judgement as to the most suitable reagent for a particular transformation;
- describe and explain strategies for the synthesis of enantiopure compounds;
- rationalise known synthetic routes to complex organic molecules;
- After attending the medicinal chemistry lecture courses, students should be able to:
- classify drugs according to their site and mode of action and critically discuss the relationships between structure and activity;
- describe methods by which drugs may be discovered, optimised and formulated;
- use molecular modelling packages to predict the mode of action of certain classes of compounds;
- After attending the macromolecular chemitry lecture courses, students should be able to:
- understand the quantitative description of the three dimensional distribution of polymer molecules and use this description to explain retractive forces in elastomers;
- distinguish between major synthetic routes to polymer molecules and describe the characteristic features of each;
- distinguish between amorphous and semi-crystalline polymers and identify molecular features that promote crystallinity. Explain the role of non-metal and transition metal based reagents and catalysts in organic synthesis.
Subject-specific Skills
Key Skills
Modes of Teaching, Learning and Assessment and how these contribute to the learning outcomes of the module
- Facts and new concepts are introduced in the lecture courses.
- Students' knowledge is tested by examination.
- Undergraduates are aided in the learning process by workshops where they attempt sample problems and office hours where staff are available to answer any queries about the lecture courses.
Teaching Methods and Learning Hours
| Activity | Number | Frequency | Duration | Total Hours | Attendance Monitored |
|---|---|---|---|---|---|
| Lectures | 36 | 1 Hour | 36 | ||
| Seminars | 4 | 1 Hour | 4 | ||
| Other (office hour) | 6 | 1 Hour | 6 | ||
| Preparation and Reading | 154 | ||||
| Total | 200 |
Summative Assessment
| Component | Component Weighting | Element | Length/Duration | Element Weighting | Resit Opportunity |
|---|---|---|---|---|---|
| Examination | 100% | examination 1 | 1.5 hours | 50% | |
| examination 2 | 1.5 hours | 50% |
Formative Assessment
Workshop problems.
Students who do not attend monitored activities shown under Teaching Methods
and Learning Hours, or who fail to complete the summative or formative
assessment(s) specified above, may be subject to the Academic Progress
procedures defined in the University's General Regulation V, and may be
required to leave the University.