This is an archived handbook for a previous year. The current undergraduate and postgraduate handbooks can be viewed using the links above.
Undergraduate Handbook 2016-2017 (archived)
Module CHEM4211: BIOACTIVE CHEMISTRY 4
Department: Chemistry
CHEM4211: BIOACTIVE CHEMISTRY 4
| Type | Level | Credits | Availability | Module Cap | Location |
|---|---|---|---|---|---|
| Tied | 4 | 20 | Available in 2016/2017 | Durham |
Tied To
Pre-requisites
- Bioactive Chemistry 3 (CHEM3211), Advanced Organic Chemistry (CHEM3117) AND Biological Chemistry (CHEM2051).
Corequisites
- Research Skills (CHEM4081).
Excluded Combinations
- Core Chemistry 4 (CHEM4311) AND Contemporary Chemistry (CHEM4321).
Aims
- To build on material taught at level three and provide students with an advanced overview of more specialised areas.
Content
- Modern organic synthesis: asymmetric synthesis; applied organic synthesis.
- Medicinal chemistry and Catalysis: Medicinal Chemistry, drug classifications; molecular targets for drug action; pharmacokinetics and pharmacodynamics; strategies for drug discovery and development; computational chemistry; Applied Catalysis and Organocatalysis.
Learning Outcomes
Subject-specific Knowledge
- appreciate the problems involved in target synthesis of organic molecules, apply retrosynthetic analysis to their synthesis and make an informed judgement as to the most suitable reagent for a particular transformation;
- describe and explain strategies for the synthesis of enantiopure compounds;
- rationalise known synthetic routes to complex organic molecules;
- classify drugs according to their site and mode of action and critically discuss the relationships between structure and activity;
- describe methods by which drugs may be discovered, optimised and formulated;
- understand the importance of solid-state forms and their characterisation for drug pharmacokinetics and patenting.
Subject-specific Skills
Key Skills
Modes of Teaching, Learning and Assessment and how these contribute to the learning outcomes of the module
- Facts and new concepts are introduced in the lecture courses.
- Students' knowledge is tested by examination.
- Undergraduates are aided in the learning process by workshops where they attempt sample problems and office hours where staff are available to answer any queries about the lecture courses.
Teaching Methods and Learning Hours
| Activity | Number | Frequency | Duration | Total Hours | Attendance Monitored |
|---|---|---|---|---|---|
| Lectures | 36 | 1 Hour | 36 | ||
| Seminars | 4 | 1 Hour | 4 | Yes | |
| Office hours | 6 | 1 Hour | 6 | ||
| Preparation and Reading | 154 | ||||
| Total | 200 |
Summative Assessment
| Component | Component Weighting | Element | Length/Duration | Element Weighting | Resit Opportunity |
|---|---|---|---|---|---|
| Examination | 100% | examination 1 | 1.5 hours | 50% | |
| examination 2 | 1.5 hours | 50% |
Formative Assessment
Workshop problems.
Students who do not attend monitored activities shown under Teaching Methods
and Learning Hours, or who fail to complete the summative or formative
assessment(s) specified above, may be subject to the Academic Progress
procedures defined in the University's General Regulation V, and may be
required to leave the University.