Module ENGI4647: Tissue Engineering 4

Department: Engineering

ENGI4647: Tissue Engineering 4

Prerequisites

• None

Corequisites

• As specified in programme regulations.

Excluded Combination of Modules

• As specified in programme regulations.

Aims

• To introduce tissue engineering and regenerative medicine principles.
• To present the engineering methods contributing to the interdisciplinary area of tissue engineering.
• To explore the significance of microenvironmental factors in tissue development.
• To allow for identifying suitable tissue engineering approaches for specific applications.

Content

• Overview of various tissue engineering techniques and applications.
• The role of microenvironmental factors and mechanical forces in cell behaviour.
• Cell and tissue culture approaches in tissue engineering.
• Bioreactors for tissue engineering.
• Biocompatible materials and cell-material interactions.
• Tissue scaffolds and fabrication techniques in tissue engineering.
• Delivery strategies in regenerative medicine.
• Mathematical and computational modelling in tissue engineering.

Learning Outcomes

• A knowledge of the status of tissue engineering, its challenges, limitations, and prospects.
• An understanding of the importance of the biophysical microenvironment in cell behaviour, and how this knowledge can be applied to tissue engineering.
• An understanding of the design principles for designing scaffolds and bioreactors.
• An appreciation of the challenges of regenerative medicine.

• Ability to apply fundamental engineering concepts in the field of tissue engineering.
• Capacity to quantify the key biophysical parameters pertaining to cells and tissues.
• Determination of the forces and transport phenomena in engineered biological systems.
• Awareness of future developments in tissue engineering and regenerative medicine.

• Capacity for independent self-learning within the bounds of professional practice.
• Mathematical and numerical skills appropriate for an engineer.
• Skills to combine interdisciplinary biological and engineering concepts relevant to the application of advanced tissue engineering problems.
• Develop skills to critically analyse the scientific literature of tissue engineering and formulate informed opinions that can be communicated effectively.

Modes of Teaching, Learning and Assessment and how these contribute to the learning outcomes of the module

• The module content is delivered in lectures and is reinforced by self-learning sessions and formative problem sheets, equipping students with the required problem-solving capability.
• Students are encouraged to engage with staff Office Hours for one‑to‑one or small‑group discussion of any aspect of the module. These sessions are offered weekly during teaching, timings are published on Learn Ultra.
• Written timed examinations are appropriate because of the range of topics covered in this module and allow students to demonstrate their knowledge and analysis of bioengineering scenarios independently.

Teaching Methods and Learning Hours

Summative Assessment

Formative Assessment:

■ Students who do not attend monitored activities shown under Teaching Methods and Learning Hours, or who fail to complete the summative or formative assessment(s) specified above, may be subject to the Academic Progress procedures defined in the University's General Regulation V, and may be required to leave the University.